2zaz: Difference between revisions

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[[Image:2zaz.jpg|left|200px]]<br /><applet load="2zaz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2zaz.jpg|left|200px]]
caption="2zaz, resolution 1.800&Aring;" />
 
'''Crystal structure of P38 in complex with 4-anilino quinoline inhibitor'''<br />
{{Structure
|PDB= 2zaz |SIZE=350|CAPTION= <scene name='initialview01'>2zaz</scene>, resolution 1.800&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GK1:'>GK1</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24]
|GENE=
}}
 
'''Crystal structure of P38 in complex with 4-anilino quinoline inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ZAZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=GK1:'>GK1</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAZ OCA].  
2ZAZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAZ OCA].  


==Reference==
==Reference==
Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode., Angell RM, Bamborough P, Cleasby A, Cockerill SG, Jones KL, Mooney CJ, Somers DO, Walker AL, Bioorg Med Chem Lett. 2008 Jan 1;18(1):318-23. Epub 2007 Nov 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18006306 18006306]
Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode., Angell RM, Bamborough P, Cleasby A, Cockerill SG, Jones KL, Mooney CJ, Somers DO, Walker AL, Bioorg Med Chem Lett. 2008 Jan 1;18(1):318-23. Epub 2007 Nov 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18006306 18006306]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
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[[Category: transferase]]
[[Category: transferase]]


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