2zcq: Difference between revisions

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New page: left|200px<br /><applet load="2zcq" size="350" color="white" frame="true" align="right" spinBox="true" caption="2zcq, resolution 2.38Å" /> '''Crystal structure of...
 
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[[Image:2zcq.jpg|left|200px]]<br /><applet load="2zcq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2zcq.jpg|left|200px]]
caption="2zcq, resolution 2.38&Aring;" />
 
'''Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-652'''<br />
{{Structure
|PDB= 2zcq |SIZE=350|CAPTION= <scene name='initialview01'>2zcq</scene>, resolution 2.38&Aring;
|SITE= <scene name='pdbsite=AC1:B65+Binding+Site+For+Residue+A+451'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+A+452'>AC2</scene> and <scene name='pdbsite=AC3:Mg+Binding+Site+For+Residue+A+453'>AC3</scene>
|LIGAND= <scene name='pdbligand=B65:'>B65</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
|ACTIVITY=
|GENE= CrtM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])
}}
 
'''Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-652'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ZCQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus] with <scene name='pdbligand=B65:'>B65</scene> and <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:B65+Binding+Site+For+Residue+A+451'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+A+452'>AC2</scene> and <scene name='pdbsite=AC3:Mg+Binding+Site+For+Residue+A+453'>AC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZCQ OCA].  
2ZCQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZCQ OCA].  


==Reference==
==Reference==
A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence., Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E, Science. 2008 Mar 7;319(5868):1391-4. Epub 2008 Feb 14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18276850 18276850]
A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence., Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E, Science. 2008 Mar 7;319(5868):1391-4. Epub 2008 Feb 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18276850 18276850]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: transferase]]
[[Category: transferase]]


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