357d: Difference between revisions
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[[Image:357d.gif|left|200px]] | [[Image:357d.gif|left|200px]] | ||
'''3.5 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA''' | {{Structure | ||
|PDB= 357d |SIZE=350|CAPTION= <scene name='initialview01'>357d</scene>, resolution 3.500Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=HG:MERCURY (II) ION'>HG</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''3.5 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
357D is a [ | 357D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=357D OCA]. | ||
==Reference== | ==Reference== | ||
Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:[http:// | Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9393863 9393863] | ||
[[Category: ]] | [[Category: ]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: u-rna]] | [[Category: u-rna]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:54:54 2008'' | ||
Revision as of 16:54, 20 March 2008
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| 357d, resolution 3.500Å | |||||||||||||
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| Ligands: | MG and HG | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
3.5 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA
Overview
Two new RNA structures portray how non-Watson-Crick base pairs and metal ions can produce a unique RNA shape suitable for recognition by proteins. The crystal structures of a 62 nt domain of E. coli 5S ribosomal RNA and a duplex dodecamer encompassing an internal loop E have been determined at 3.0 and 1.5 A, respectively. This loop E region is distorted by three "cross-strand purine stacks" and three novel, water-mediated noncanonical base pairs and stabilized by a four metal ion zipper. These features give its minor groove a unique hydrogen-bonding surface and make the adjacent major groove wide enough to permit recognition by the ribosomal protein L25, which is expected to bind to this surface.
About this Structure
357D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:9393863 [[Category: ]]
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