4d60: Difference between revisions
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''' | ==Structure of a dimeric Plasmodium falciparum profilin mutant== | ||
<StructureSection load='4d60' size='340' side='right' caption='[[4d60]], [[Resolution|resolution]] 3.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4d60]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D60 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d60 RCSB], [http://www.ebi.ac.uk/pdbsum/4d60 PDBsum]</span></td></tr> | |||
</table> | |||
[[Category: | == Function == | ||
[[Category: Kallio, J | [[http://www.uniprot.org/uniprot/PROF_PLAFX PROF_PLAFX]] Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers.<ref>PMID:19000816</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bhargav, S P]] | |||
[[Category: Kallio, J P]] | |||
[[Category: Kursula, I]] | [[Category: Kursula, I]] | ||
[[Category: Kursula, P]] | [[Category: Kursula, P]] | ||
[[Category: Torda, A]] | [[Category: Torda, A]] | ||
[[Category: | [[Category: Vahokoski, J]] | ||
[[Category: Actin binding]] | |||
[[Category: Domain swapping]] | |||
[[Category: Structural protein]] | |||
Revision as of 12:42, 3 June 2015
Structure of a dimeric Plasmodium falciparum profilin mutant
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