4y21: Difference between revisions
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''' | ==Crystal Structure of Munc13-1 MUN domain== | ||
<StructureSection load='4y21' size='340' side='right' caption='[[4y21]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4y21]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y21 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y21 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y21 RCSB], [http://www.ebi.ac.uk/pdbsum/4y21 PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[Category: | [[http://www.uniprot.org/uniprot/UN13A_RAT UN13A_RAT]] Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. Also involved in secretory granule priming in insulin secretion.<ref>PMID:9697857</ref> <ref>PMID:11343654</ref> <ref>PMID:11792326</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Kang, L J]] | |||
[[Category: Ma, C]] | |||
[[Category: Rizo, J]] | [[Category: Rizo, J]] | ||
[[Category: Sheng, Y]] | [[Category: Sheng, Y]] | ||
[[Category: Wang, S]] | [[Category: Wang, S]] | ||
[[Category: | [[Category: Wu, L J]] | ||
[[Category: | [[Category: Xu, T]] | ||
[[Category: Yang, X Y]] | |||
[[Category: Zhang, M]] | [[Category: Zhang, M]] | ||
[[Category: Zou, W | [[Category: Zhang, R G]] | ||
[[Category: | [[Category: Zou, W J]] | ||
[[Category: Catchr]] | |||
[[Category: Exocytosis]] | |||
[[Category: Helical bundle]] | |||
Revision as of 14:10, 10 June 2015
Crystal Structure of Munc13-1 MUN domain
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