3bpl: Difference between revisions

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[[Image:3bpl.jpg|left|200px]]<br /><applet load="3bpl" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3bpl.jpg|left|200px]]
caption="3bpl, resolution 2.93&Aring;" />
 
'''Crystal structure of the IL4-IL4R-Common Gamma ternary complex'''<br />
{{Structure
|PDB= 3bpl |SIZE=350|CAPTION= <scene name='initialview01'>3bpl</scene>, resolution 2.93&Aring;
|SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+B+901'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+B+902'>AC2</scene>, <scene name='pdbsite=AC3:Nag+Binding+Site+For+Residue+B+911'>AC3</scene>, <scene name='pdbsite=AC4:Fuc+Binding+Site+For+Residue+B+913'>AC4</scene>, <scene name='pdbsite=AC5:Nag+Binding+Site+For+Residue+C+921'>AC5</scene>, <scene name='pdbsite=AC6:Nag+Binding+Site+For+Residue+C+931'>AC6</scene> and <scene name='pdbsite=AC7:Nag+Binding+Site+For+Residue+C+941'>AC7</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>
|ACTIVITY=
|GENE= IL4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), IL4R, 582J2.1, IL4RA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), IL2RG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the IL4-IL4R-Common Gamma ternary complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
3BPL is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+B+901'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+B+902'>AC2</scene>, <scene name='pdbsite=AC3:Nag+Binding+Site+For+Residue+B+911'>AC3</scene>, <scene name='pdbsite=AC4:Fuc+Binding+Site+For+Residue+B+913'>AC4</scene>, <scene name='pdbsite=AC5:Nag+Binding+Site+For+Residue+C+921'>AC5</scene>, <scene name='pdbsite=AC6:Nag+Binding+Site+For+Residue+C+931'>AC6</scene> and <scene name='pdbsite=AC7:Nag+Binding+Site+For+Residue+C+941'>AC7</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPL OCA].  
3BPL is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPL OCA].  


==Reference==
==Reference==
Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System., Laporte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, Garcia KC, Cell. 2008 Jan 25;132(2):259-272. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18243101 18243101]
Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System., Laporte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, Garcia KC, Cell. 2008 Jan 25;132(2):259-272. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18243101 18243101]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: transmembrane]]
[[Category: transmembrane]]


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