3bpr: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,493 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,493 edits
No edit summary
Line 1: Line 1:
[[Image:3bpr.jpg|left|200px]]<br /><applet load="3bpr" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3bpr.jpg|left|200px]]
caption="3bpr, resolution 2.80&Aring;" />
 
'''Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52'''<br />
{{Structure
|PDB= 3bpr |SIZE=350|CAPTION= <scene name='initialview01'>3bpr</scene>, resolution 2.80&Aring;
|SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Residue+B+1'>AC1</scene>, <scene name='pdbsite=AC2:Cl+Binding+Site+For+Residue+C+133'>AC2</scene>, <scene name='pdbsite=AC3:Olp+Binding+Site+For+Residue+A+900'>AC3</scene>, <scene name='pdbsite=AC4:Olp+Binding+Site+For+Residue+B+900'>AC4</scene>, <scene name='pdbsite=AC5:Olp+Binding+Site+For+Residue+C+900'>AC5</scene> and <scene name='pdbsite=AC6:Olp+Binding+Site+For+Residue+D+900'>AC6</scene>
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=OLP:2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE'>OLP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1]
|GENE= MERTK, MER ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52'''
 


==About this Structure==
==About this Structure==
3BPR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=OLP:'>OLP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] Known structural/functional Sites: <scene name='pdbsite=AC1:Na+Binding+Site+For+Residue+B+1'>AC1</scene>, <scene name='pdbsite=AC2:Cl+Binding+Site+For+Residue+C+133'>AC2</scene>, <scene name='pdbsite=AC3:Olp+Binding+Site+For+Residue+A+900'>AC3</scene>, <scene name='pdbsite=AC4:Olp+Binding+Site+For+Residue+B+900'>AC4</scene>, <scene name='pdbsite=AC5:Olp+Binding+Site+For+Residue+C+900'>AC5</scene> and <scene name='pdbsite=AC6:Olp+Binding+Site+For+Residue+D+900'>AC6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPR OCA].  
3BPR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPR OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
Line 36: Line 45:
[[Category: sgc]]
[[Category: sgc]]
[[Category: signal]]
[[Category: signal]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
[[Category: transferase]]
[[Category: transferase]]
Line 43: Line 52:
[[Category: vision]]
[[Category: vision]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:06:55 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:00:31 2008''

Revision as of 17:00, 20 March 2008

File:3bpr.jpg


Drag the structure with the mouse to rotate
3bpr, resolution 2.80Å
Sites: AC1, AC2, AC3, AC4, AC5 and AC6
Ligands: NA, CL and OLP
Gene: MERTK, MER (Homo sapiens)
Activity: Receptor protein-tyrosine kinase, with EC number 2.7.10.1
Coordinates: save as pdb, mmCIF, xml



Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52


About this Structure

3BPR is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 19:00:31 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=3bpr&oldid=241116"