3bq5: Difference between revisions

[[Image:3bq5.jpg|left|200px]]<br /><applet load="3bq5" size="350" color="white" frame="true" align="right" spinBox="true"

caption="3bq5, resolution 2.0&Aring;" />

'''Crystal Structure of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ and Homocysteine (Monoclinic)'''<br />

3BQ5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=HCS:'>HCS</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] Known structural/functional Sites: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+800'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+B+801'>AC2</scene>, <scene name='pdbsite=AC3:Hcs+Binding+Site+For+Residue+A+802'>AC3</scene>, <scene name='pdbsite=AC4:Edo+Binding+Site+For+Residue+A+804'>AC4</scene>, <scene name='pdbsite=AC5:Hcs+Binding+Site+For+Residue+B+803'>AC5</scene> and <scene name='pdbsite=AC6:Edo+Binding+Site+For+Residue+B+805'>AC6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQ5 OCA].  

Metal active site elasticity linked to activation of homocysteine in methionine synthases., Koutmos M, Pejchal R, Bomer TM, Matthews RG, Smith JL, Ludwig ML, Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3286-91. Epub 2008 Feb 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18296644 18296644]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Mar 14 09:38:57 2008''