3c0z: Difference between revisions

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New page: left|200px<br /><applet load="3c0z" size="350" color="white" frame="true" align="right" spinBox="true" caption="3c0z, resolution 2.10Å" /> '''Crystal structure of...
 
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[[Image:3c0z.jpg|left|200px]]<br /><applet load="3c0z" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3c0z.jpg|left|200px]]
caption="3c0z, resolution 2.10&Aring;" />
 
'''Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with SAHA'''<br />
{{Structure
|PDB= 3c0z |SIZE=350|CAPTION= <scene name='initialview01'>3c0z</scene>, resolution 2.10&Aring;
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+101'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+102'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+B+101'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+B+102'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+C+101'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+C+102'>AC6</scene>, <scene name='pdbsite=AC7:K+Binding+Site+For+Residue+A+201'>AC7</scene>, <scene name='pdbsite=AC8:K+Binding+Site+For+Residue+A+202'>AC8</scene>, <scene name='pdbsite=AC9:K+Binding+Site+For+Residue+B+201'>AC9</scene>, <scene name='pdbsite=BC1:K+Binding+Site+For+Residue+B+202'>BC1</scene>, <scene name='pdbsite=BC2:K+Binding+Site+For+Residue+C+201'>BC2</scene>, <scene name='pdbsite=BC3:K+Binding+Site+For+Residue+C+202'>BC3</scene>, <scene name='pdbsite=BC4:Shh+Binding+Site+For+Residue+A+301'>BC4</scene>, <scene name='pdbsite=BC5:Shh+Binding+Site+For+Residue+B+301'>BC5</scene> and <scene name='pdbsite=BC6:Shh+Binding+Site+For+Residue+C+301'>BC6</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> and <scene name='pdbligand=SHH:OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE'>SHH</scene>
|ACTIVITY=
|GENE= HDAC7A, HDAC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with SAHA'''
 


==About this Structure==
==About this Structure==
3C0Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=SHH:'>SHH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2PQO. Known structural/functional Sites: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+101'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+102'>AC2</scene>, <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+B+101'>AC3</scene>, <scene name='pdbsite=AC4:Zn+Binding+Site+For+Residue+B+102'>AC4</scene>, <scene name='pdbsite=AC5:Zn+Binding+Site+For+Residue+C+101'>AC5</scene>, <scene name='pdbsite=AC6:Zn+Binding+Site+For+Residue+C+102'>AC6</scene>, <scene name='pdbsite=AC7:K+Binding+Site+For+Residue+A+201'>AC7</scene>, <scene name='pdbsite=AC8:K+Binding+Site+For+Residue+A+202'>AC8</scene>, <scene name='pdbsite=AC9:K+Binding+Site+For+Residue+B+201'>AC9</scene>, <scene name='pdbsite=BC1:K+Binding+Site+For+Residue+B+202'>BC1</scene>, <scene name='pdbsite=BC2:K+Binding+Site+For+Residue+C+201'>BC2</scene>, <scene name='pdbsite=BC3:K+Binding+Site+For+Residue+C+202'>BC3</scene>, <scene name='pdbsite=BC4:Shh+Binding+Site+For+Residue+A+301'>BC4</scene>, <scene name='pdbsite=BC5:Shh+Binding+Site+For+Residue+B+301'>BC5</scene> and <scene name='pdbsite=BC6:Shh+Binding+Site+For+Residue+C+301'>BC6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C0Z OCA].  
3C0Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2PQO. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C0Z OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 30: Line 39:
[[Category: repressor]]
[[Category: repressor]]
[[Category: sgc]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
[[Category: transcription]]
[[Category: transcription]]
[[Category: transcription regulation]]
[[Category: transcription regulation]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:08:06 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:02:04 2008''
Retrieved from "https://proteopedia.org/3c0z"