Tissue factor

spinqualitylabelsall models Structure of human tissue factor (dark green) complex with coagulation factor VIIa heavy chain (red) and light chain (aqua) and Ca+2 ion (green) (PDB code 2aer). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Tissue factor (TF) is a high-affinity receptor for the blood coagulation factor VII. The TF/factor VII complex is responsible for the initiation of the coagulation protease cascade.

3D structures of tissue factor

Updated on 21-June-2015

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• Tissue factor
  • 1a21 – rTF extracellular domain – rabbit
    
  • 2hft, 1boy, 1tfh – hTF extracellular domain – human
    
• Tissue factor binary complex
  • 1dan, 1j9c, 1w0y – hTF extracellular domain + factor VIIA
    
  • 1o5d – hTF extracellular domain (mutant) + factor VIIA
    
  • 1ahw, 1jps, 1uj3, 4m7l – hTF extracellular domain + antibody
    
• Tissue factor ternary complex with coagulation factor VIIa and inhibitor
  • 1fak – hTF extracellular domain + factor VIIA + BPTI
    
  • 1z6j, 1w2k, 2b7d, 2f9b, 2flb, 2a2q, 2aer, 2fir, 2aei, 2c4f, 2flr, 2ec9, 2zp0, 2zzu, 3th2, 4ibl – hTF extracellular domain + factor VIIA + inhibitor
    
  • 1wqv, 1wss, 1wtg, 1wun, 1wv7, 2b8o, 2puq, 3ela, 2zwl, 3th3, 3th4 – hTF extracellular domain + factor VIIA + peptide mimetic inhibitor
    

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