Complement C5: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='3pvm' size='340' side='right' caption='Human complement C5 complex with cobra venom factor (PDB code 3pvm)' scene=''> '''Complement C5''' (CC5) is the fifth co... |
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<StructureSection load='3pvm' size='340' side='right' caption='Human complement C5 complex (grey and pink) with cobra venom factor (green and yellow) (PDB code [[3pvm]])' scene=''> | |||
<StructureSection load='3pvm' size='340' side='right' caption='Human complement C5 complex with cobra venom factor (PDB code [[3pvm]])' scene=''> | |||
'''Complement C5''' (CC5) is the fifth component of the complement system. The complement system is part of the innate immune system. CC5 is composed of α chain (C5a) and β chain (C5b). Proteoplytic degradation of CC5 produces '''anaphylatoxin''' which is a mediator of local inflammatory process. The C terminal domain of CC5 (residues 1530-1676) is homologous to a domain in netrins and is named '''C345C'''. Activation of CC5 by C5 convertase initiates the assembly of the C5 to C9 components into the membrane attack complex. | '''Complement C5''' (CC5) is the fifth component of the complement system. The complement system is part of the innate immune system. CC5 is composed of α chain (C5a) and β chain (C5b). Proteoplytic degradation of CC5 produces '''anaphylatoxin''' which is a mediator of local inflammatory process. The C terminal domain of CC5 (residues 1530-1676) is homologous to a domain in netrins and is named '''C345C'''. Activation of CC5 by C5 convertase initiates the assembly of the C5 to C9 components into the membrane attack complex. | ||
