3grt: Difference between revisions

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[[Image:3grt.jpg|left|200px]]<br /><applet load="3grt" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3grt.jpg|left|200px]]
caption="3grt, resolution 2.50&Aring;" />
 
'''HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, OXIDIZED TRYPANOTHIONE COMPLEX'''<br />
{{Structure
|PDB= 3grt |SIZE=350|CAPTION= <scene name='initialview01'>3grt</scene>, resolution 2.50&Aring;
|SITE= <scene name='pdbsite=S1:The+Active+Site+HIS+(HIS+467)+Is+From+The+Other+Subunit'>S1</scene>
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene> and <scene name='pdbligand=TS2:2-AMINO-4-[4-(4-AMINO-4-CARBOXY-BUTYRYLAMINO)-5,8,19,22-TETRAOXO-1,2-DITHIA-6,9,13,18,21-PENTAAZA-CYCLOTETRACOS-23-YLCARBAMOYL]-BUTYRIC ACID'>TS2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_1.8.1.7 Transferred entry: 1.8.1.7], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.4.2 1.6.4.2]
|GENE=
}}
 
'''HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, OXIDIZED TRYPANOTHIONE COMPLEX'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
3GRT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FAD:'>FAD</scene> and <scene name='pdbligand=TS2:'>TS2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Transferred_entry:_1.8.1.7 Transferred entry: 1.8.1.7], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.4.2 1.6.4.2] Known structural/functional Site: <scene name='pdbsite=S1:The+Active+Site+HIS+(HIS+467)+Is+From+The+Other+Subunit'>S1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GRT OCA].  
3GRT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GRT OCA].  


==Reference==
==Reference==
Redox enzyme engineering: conversion of human glutathione reductase into a trypanothione reductase., Bradley M, Bucheler US, Walsh CT, Biochemistry. 1991 Jun 25;30(25):6124-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2059620 2059620]
Redox enzyme engineering: conversion of human glutathione reductase into a trypanothione reductase., Bradley M, Bucheler US, Walsh CT, Biochemistry. 1991 Jun 25;30(25):6124-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2059620 2059620]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]


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