4ytg: Difference between revisions

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'''Unreleased structure'''
==Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) mutant C351A in complex with dipeptide Met-Arg.==
 
<StructureSection load='4ytg' size='340' side='right' caption='[[4ytg]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
The entry 4ytg is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4ytg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YTG FirstGlance]. <br>
Authors: Goulas, T., Mizgalska, D., Garcia-Ferrer, I., Kantyka, T., Guevara, T., Szmigielski, B., Sroka, A., Millan, C., Uson, I., Veillard, F., Potempa, B., Mydel, P., Sola, M., Potempa, J., Gomis-Ruth, F.X.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yt9|4yt9]]</td></tr>
Description: Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) mutant C351A in complex with dipeptide Met-Arg.
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ytg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ytg RCSB], [http://www.ebi.ac.uk/pdbsum/4ytg PDBsum]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PAD_PORGI PAD_PORGI]] Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth.<ref>PMID:10377098</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Porphyromonas gingivalis]]
[[Category: Garcia-Ferrer, I]]
[[Category: Garcia-Ferrer, I]]
[[Category: Gomis-Ruth, F.X]]
[[Category: Gomis-Ruth, F X]]
[[Category: Uson, I]]
[[Category: Goulas, T]]
[[Category: Goulas, T]]
[[Category: Guevara, T]]
[[Category: Kantyka, T]]
[[Category: Millan, C]]
[[Category: Mizgalska, D]]
[[Category: Mydel, P]]
[[Category: Potempa, B]]
[[Category: Potempa, B]]
[[Category: Potempa, J]]
[[Category: Potempa, J]]
[[Category: Veillard, F]]
[[Category: Sola, M]]
[[Category: Sola, M]]
[[Category: Mydel, P]]
[[Category: Millan, C]]
[[Category: Sroka, A]]
[[Category: Sroka, A]]
[[Category: Guevara, T]]
[[Category: Mizgalska, D]]
[[Category: Kantyka, T]]
[[Category: Szmigielski, B]]
[[Category: Szmigielski, B]]
[[Category: Uson, I]]
[[Category: Veillard, F]]
[[Category: Citrullination]]
[[Category: Hydrolase]]
[[Category: Peptidylarginine deiminase]]
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