3znb: Difference between revisions

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[[Image:3znb.jpg|left|200px]]<br /><applet load="3znb" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3znb.jpg|left|200px]]
caption="3znb, resolution 2.7&Aring;" />
 
'''METALLO-BETA-LACTAMASE (ZN, HG-BOUND FORM)'''<br />
{{Structure
|PDB= 3znb |SIZE=350|CAPTION= <scene name='initialview01'>3znb</scene>, resolution 2.7&Aring;
|SITE= <scene name='pdbsite=HG:Zn2+Was+Ejected+And+The+Hg+Is+Bound+In+A+Different+Position'>HG</scene>, <scene name='pdbsite=NA:Deduced+From+The+Coordination+In+The+Native+Structure.+N+...'>NA</scene> and <scene name='pdbsite=ZN:The+Zn+Is+Located+In+The+Same+Position+As+Zn1+In+The+Nat+...'>ZN</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene> and <scene name='pdbligand=NA:SODIUM ION'>NA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]
|GENE= CCRA3 (WITHOUT SIGNAL SEQUENCE) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=817 Bacteroides fragilis])
}}
 
'''METALLO-BETA-LACTAMASE (ZN, HG-BOUND FORM)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
3ZNB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_fragilis Bacteroides fragilis] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=HG:'>HG</scene> and <scene name='pdbligand=NA:'>NA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Known structural/functional Sites: <scene name='pdbsite=HG:Zn2+Was+Ejected+And+The+Hg+Is+Bound+In+A+Different+Position'>HG</scene>, <scene name='pdbsite=NA:Deduced+From+The+Coordination+In+The+Native+Structure.+N+...'>NA</scene> and <scene name='pdbsite=ZN:The+Zn+Is+Located+In+The+Same+Position+As+Zn1+In+The+Nat+...'>ZN</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZNB OCA].  
3ZNB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_fragilis Bacteroides fragilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZNB OCA].  


==Reference==
==Reference==
Crystal structures of the cadmium- and mercury-substituted metallo-beta-lactamase from Bacteroides fragilis., Concha NO, Rasmussen BA, Bush K, Herzberg O, Protein Sci. 1997 Dec;6(12):2671-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9416622 9416622]
Crystal structures of the cadmium- and mercury-substituted metallo-beta-lactamase from Bacteroides fragilis., Concha NO, Rasmussen BA, Bush K, Herzberg O, Protein Sci. 1997 Dec;6(12):2671-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9416622 9416622]
[[Category: Bacteroides fragilis]]
[[Category: Bacteroides fragilis]]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
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[[Category: zinc]]
[[Category: zinc]]


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