4aig: Difference between revisions

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[[Image:4aig.gif|left|200px]]<br /><applet load="4aig" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:4aig.gif|left|200px]]
caption="4aig, resolution 2.00&Aring;" />
 
'''ADAMALYSIN II WITH PHOSPHONATE INHIBITOR'''<br />
{{Structure
|PDB= 4aig |SIZE=350|CAPTION= <scene name='initialview01'>4aig</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=FLX:N-[(FURAN-2-YL)CARBONYL]-(S)-LEUCYL-(R)-[1-AMINO-2(1H-INDOL-3-YL)ETHYL]-PHOSPHONIC ACID'>FLX</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adamalysin Adamalysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.46 3.4.24.46]
|GENE=
}}
 
'''ADAMALYSIN II WITH PHOSPHONATE INHIBITOR'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
4AIG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Crotalus_adamanteus Crotalus adamanteus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=FLX:'>FLX</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adamalysin Adamalysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.46 3.4.24.46] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AIG OCA].  
4AIG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Crotalus_adamanteus Crotalus adamanteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AIG OCA].  


==Reference==
==Reference==
2 angstrom X-ray structure of adamalysin II complexed with a peptide phosphonate inhibitor adopting a retro-binding mode., Cirilli M, Gallina C, Gavuzzo E, Giordano C, Gomis-Ruth FX, Gorini B, Kress LF, Mazza F, Paradisi MP, Pochetti G, Politi V, FEBS Lett. 1997 Dec 1;418(3):319-22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9428736 9428736]
2 angstrom X-ray structure of adamalysin II complexed with a peptide phosphonate inhibitor adopting a retro-binding mode., Cirilli M, Gallina C, Gavuzzo E, Giordano C, Gomis-Ruth FX, Gorini B, Kress LF, Mazza F, Paradisi MP, Pochetti G, Politi V, FEBS Lett. 1997 Dec 1;418(3):319-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9428736 9428736]
[[Category: Adamalysin]]
[[Category: Adamalysin]]
[[Category: Crotalus adamanteus]]
[[Category: Crotalus adamanteus]]
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[[Category: zinc protease]]
[[Category: zinc protease]]


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