4csm: Difference between revisions

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[[Image:4csm.gif|left|200px]]<br /><applet load="4csm" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:4csm.gif|left|200px]]
caption="4csm, resolution 2.8&Aring;" />
 
'''YEAST CHORISMATE MUTASE + TYR + ENDOOXABICYCLIC INHIBITOR'''<br />
{{Structure
|PDB= 4csm |SIZE=350|CAPTION= <scene name='initialview01'>4csm</scene>, resolution 2.8&Aring;
|SITE= <scene name='pdbsite=ACT:Active+Site'>ACT</scene> and <scene name='pdbsite=REG:Regulatory+Binding+Site+For+TRP+And+TYR'>REG</scene>
|LIGAND= <scene name='pdbligand=TYR:TYROSINE'>TYR</scene> and <scene name='pdbligand=TSA:8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID'>TSA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5]
|GENE=
}}
 
'''YEAST CHORISMATE MUTASE + TYR + ENDOOXABICYCLIC INHIBITOR'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
4CSM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=TYR:'>TYR</scene> and <scene name='pdbligand=TSA:'>TSA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] Known structural/functional Sites: <scene name='pdbsite=ACT:Active+Site'>ACT</scene> and <scene name='pdbsite=REG:Regulatory+Binding+Site+For+TRP+And+TYR'>REG</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSM OCA].  
4CSM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CSM OCA].  


==Reference==
==Reference==
Mechanisms of catalysis and allosteric regulation of yeast chorismate mutase from crystal structures., Strater N, Schnappauf G, Braus G, Lipscomb WN, Structure. 1997 Nov 15;5(11):1437-52. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9384560 9384560]
Mechanisms of catalysis and allosteric regulation of yeast chorismate mutase from crystal structures., Strater N, Schnappauf G, Braus G, Lipscomb WN, Structure. 1997 Nov 15;5(11):1437-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9384560 9384560]
[[Category: Chorismate mutase]]
[[Category: Chorismate mutase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: transition state analog]]
[[Category: transition state analog]]


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