4fiv: Difference between revisions

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[[Image:4fiv.gif|left|200px]]<br /><applet load="4fiv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:4fiv.gif|left|200px]]
caption="4fiv, resolution 1.8&Aring;" />
 
'''FIV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130'''<br />
{{Structure
|PDB= 4fiv |SIZE=350|CAPTION= <scene name='initialview01'>4fiv</scene>, resolution 1.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=LP1:4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE'>LP1</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
|GENE=
}}
 
'''FIV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
4FIV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus] with <scene name='pdbligand=LP1:'>LP1</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FIV OCA].  
4FIV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FIV OCA].  


==Reference==
==Reference==
Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV., Kervinen J, Lubkowski J, Zdanov A, Bhatt D, Dunn BM, Hui KY, Powell DJ, Kay J, Wlodawer A, Gustchina A, Protein Sci. 1998 Nov;7(11):2314-23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9827997 9827997]
Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV., Kervinen J, Lubkowski J, Zdanov A, Bhatt D, Dunn BM, Hui KY, Powell DJ, Kay J, Wlodawer A, Gustchina A, Protein Sci. 1998 Nov;7(11):2314-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9827997 9827997]
[[Category: Feline immunodeficiency virus]]
[[Category: Feline immunodeficiency virus]]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
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[[Category: retrovirus]]
[[Category: retrovirus]]


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