2mqf: Difference between revisions
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''' | ==NMR structure of spider toxin-TRTX-Hhn2b== | ||
<StructureSection load='2mqf' size='340' side='right' caption='[[2mqf]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2mqf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MQF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MQF FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mqf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mqf RCSB], [http://www.ebi.ac.uk/pdbsum/2mqf PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[Category: | [[http://www.uniprot.org/uniprot/H1A03_HAPHA H1A03_HAPHA]] Is a depressant toxin. Blocks the SCN2A/SCN1B (Nav1.2/Beta1) sodium channel receptor (IC(50) is 68 +-6 uM) and the insect sodium channel para/tipE (IC(50) is 4.3 +-0.3 uM), without altering the activation or inactivation kinetics.<ref>PMID:14675784</ref> | ||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Chin, Y K.Y]] | |||
[[Category: Klint, J K]] | |||
[[Category: Mobli, M]] | [[Category: Mobli, M]] | ||
[[Category: | [[Category: Nav1 7]] | ||
[[Category: Spider toxin]] | |||
[[Category: Toxin]] | |||
[[Category: Voltage gated ion channel]] | |||
Revision as of 13:28, 15 July 2015
NMR structure of spider toxin-TRTX-Hhn2b
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