5gds: Difference between revisions

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[[Image:5gds.gif|left|200px]]<br /><applet load="5gds" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:5gds.gif|left|200px]]
caption="5gds, resolution 2.1&Aring;" />
 
'''HIRUNORMS ARE TRUE HIRUDIN MIMETICS. THE CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN:HIRUNORM V COMPLEX'''<br />
{{Structure
|PDB= 5gds |SIZE=350|CAPTION= <scene name='initialview01'>5gds</scene>, resolution 2.1&Aring;
|SITE= <scene name='pdbsite=CAT:Catalytic+Site'>CAT</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''HIRUNORMS ARE TRUE HIRUDIN MIMETICS. THE CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN:HIRUNORM V COMPLEX'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
5GDS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Known structural/functional Site: <scene name='pdbsite=CAT:Catalytic+Site'>CAT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GDS OCA].  
5GDS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GDS OCA].  


==Reference==
==Reference==
Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex., De Simone G, Lombardi A, Galdiero S, Nastri F, Della Morte R, Staiano N, Pedone C, Bolognesi M, Pavone V, Protein Sci. 1998 Feb;7(2):243-53. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9521099 9521099]
Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex., De Simone G, Lombardi A, Galdiero S, Nastri F, Della Morte R, Staiano N, Pedone C, Bolognesi M, Pavone V, Protein Sci. 1998 Feb;7(2):243-53. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9521099 9521099]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Staiano, N.]]
[[Category: Staiano, N.]]
[[Category: NAG]]
[[Category: NAG]]
[[Category: antithrombotics]]
[[Category: antithrombotic]]
[[Category: blood coagulation]]
[[Category: blood coagulation]]
[[Category: complex (serine protease/inhibitor)]]
[[Category: complex (serine protease/inhibitor)]]
[[Category: hirudin-like binding mode]]
[[Category: hirudin-like binding mode]]
[[Category: hirunorms]]
[[Category: hirunorm]]
[[Category: thrombin]]
[[Category: thrombin]]
[[Category: thrombin synthetic inhibitors]]
[[Category: thrombin synthetic inhibitor]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:12:08 2008''
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