5tmp: Difference between revisions

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[[Image:5tmp.gif|left|200px]]<br /><applet load="5tmp" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:5tmp.gif|left|200px]]
caption="5tmp, resolution 1.98&Aring;" />
 
'''COMPLEX OF E. COLI THYMIDYLATE KINASE WITH THE BISUBSTRATE INHIBITOR AZTP5A'''<br />
{{Structure
|PDB= 5tmp |SIZE=350|CAPTION= <scene name='initialview01'>5tmp</scene>, resolution 1.98&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=Z5A:P1-(5'-ADENOSYL)P5-(5'-(3'AZIDO-3'-DEOXYTHYMIDYL))PENTAPHOSPHATE'>Z5A</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9]
|GENE=
}}
 
'''COMPLEX OF E. COLI THYMIDYLATE KINASE WITH THE BISUBSTRATE INHIBITOR AZTP5A'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
5TMP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=Z5A:'>Z5A</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TMP OCA].  
5TMP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TMP OCA].  


==Reference==
==Reference==
Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase., Lavie A, Ostermann N, Brundiers R, Goody RS, Reinstein J, Konrad M, Schlichting I, Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14045-50. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9826650 9826650]
Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase., Lavie A, Ostermann N, Brundiers R, Goody RS, Reinstein J, Konrad M, Schlichting I, Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14045-50. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9826650 9826650]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: atp:dtmp phosphotransferase]]
[[Category: atp:dtmp phosphotransferase]]


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