6pah: Difference between revisions

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[[Image:6pah.gif|left|200px]]~~<br /><applet load~~="6pah~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:6pah.gif|left|200px]]

~~caption="~~6pah, resolution 2.15Å" />

'''HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND L-DOPA (3,4-DIHYDROXYPHENYLALANINE) INHIBITOR'''~~<br />~~

{{Structure

|PDB= 6pah |SIZE=350|CAPTION= <scene name='initialview01'>6pah</scene>, resolution 2.15Å

|SITE= <scene name='pdbsite=NUL:Fe+Binding+Ligands'>NUL</scene>

|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene> and <scene name='pdbligand=DAH:3,4-DIHYDROXYPHENYLALANINE'>DAH</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1]

|GENE=

}}

'''HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND L-DOPA (3,4-DIHYDROXYPHENYLALANINE) INHIBITOR'''

==Overview==

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==About this Structure==

6PAH is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FE:'>FE</scene> and <scene name='pdbligand=DAH:'>DAH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] Known structural/functional Site: <scene name='pdbsite=NUL:Fe+Binding+Ligands'>NUL</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PAH OCA].

6PAH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PAH OCA].

==Reference==

Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution., Erlandsen H, Flatmark T, Stevens RC, Hough E, Biochemistry. 1998 Nov 10;37(45):15638-46. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~9843368 9843368]

Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution., Erlandsen H, Flatmark T, Stevens RC, Hough E, Biochemistry. 1998 Nov 10;37(45):15638-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9843368 9843368]

[[Category: Homo sapiens]]

[[Category: Phenylalanine 4-monooxygenase]]

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[[Category: oxidoreductase]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:13:51 2008''

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@@ Line 1: / Line 1: @@
-[[Image:6pah.gif|left|200px]]<br /><applet load="6pah" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:6pah.gif|left|200px]]
-caption="6pah, resolution 2.15&Aring;" />
-'''HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND L-DOPA (3,4-DIHYDROXYPHENYLALANINE) INHIBITOR'''<br />
+ {{Structure
+|PDB= 6pah |SIZE=350|CAPTION= <scene name='initialview01'>6pah</scene>, resolution 2.15&Aring;
+|SITE= <scene name='pdbsite=NUL:Fe+Binding+Ligands'>NUL</scene>
+|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene> and <scene name='pdbligand=DAH:3,4-DIHYDROXYPHENYLALANINE'>DAH</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1]
+|GENE=
+}}
+'''HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND L-DOPA (3,4-DIHYDROXYPHENYLALANINE) INHIBITOR'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-PAH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FE:'>FE</scene> and <scene name='pdbligand=DAH:'>DAH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] Known structural/functional Site: <scene name='pdbsite=NUL:Fe+Binding+Ligands'>NUL</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PAH OCA].
+PAH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PAH OCA].
 ==Reference==
-Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution., Erlandsen H, Flatmark T, Stevens RC, Hough E, Biochemistry. 1998 Nov 10;37(45):15638-46. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9843368 9843368]
+Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution., Erlandsen H, Flatmark T, Stevens RC, Hough E, Biochemistry. 1998 Nov 10;37(45):15638-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9843368 9843368]
 [[Category: Homo sapiens]]
 [[Category: Phenylalanine 4-monooxygenase]]
@@ Line 25: / Line 34: @@
 [[Category: oxidoreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:16:35 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:13:51 2008''