7tln: Difference between revisions

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[[Image:7tln.gif|left|200px]]<br /><applet load="7tln" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:7tln.gif|left|200px]]
caption="7tln, resolution 2.3&Aring;" />
 
'''STRUCTURAL ANALYSIS OF THE INHIBITION OF THERMOLYSIN BY AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR'''<br />
{{Structure
|PDB= 7tln |SIZE=350|CAPTION= <scene name='initialview01'>7tln</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=INC:2-(ACETYL-HYDROXY-AMINO)-4-METHYL-PENTANOIC ACID METHYL ESTER'>INC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27]
|GENE=
}}
 
'''STRUCTURAL ANALYSIS OF THE INHIBITION OF THERMOLYSIN BY AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
7TLN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=INC:'>INC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 6TLN. Active as [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TLN OCA].  
7TLN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. This structure supersedes the now removed PDB entry 6TLN. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TLN OCA].  


==Reference==
==Reference==
Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor., Holmes MA, Tronrud DE, Matthews BW, Biochemistry. 1983 Jan 4;22(1):236-40. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=6830761 6830761]
Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor., Holmes MA, Tronrud DE, Matthews BW, Biochemistry. 1983 Jan 4;22(1):236-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/6830761 6830761]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: hydrolase (metalloproteinase)]]
[[Category: hydrolase (metalloproteinase)]]


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