4xee: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Structure of active-like neurotensin receptor==

~~The entry~~ 4xee is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4xee]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEE OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XEE FirstGlance].

~~Authors~~: ~~Krumm~~, B.E., ~~White~~, J.F., ~~Shah, P~~.~~, Grisshammer, R~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4xes|4xes]]</td></tr>

~~Description~~: ~~Structure~~ of ~~active-like neurotensin receptor~~

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xee OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xee RCSB], [http://www.ebi.ac.uk/pdbsum/4xee PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/NTR1_RAT NTR1_RAT]] Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. [[http://www.uniprot.org/uniprot/NEUT_RAT NEUT_RAT]] Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.

__TOC__

</StructureSection>

[[Category: Lysozyme]]

[[Category: Grisshammer, R]]

[[Category: Krumm, B E]]

[[Category: Shah, P]]

[[Category: ~~Krumm~~, ~~B.E~~]]

[[Category: White, J F]]

[[Category: ~~Grisshammer, R~~]]

[[Category: G protein-coupled receptor]]

[[Category: ~~White, J.F~~]]

[[Category: Gpcr]]

[[Category: Hydrolase]]

[[Category: Membrane protein]]

[[Category: Neurotensin receptor]]

[[Category: Ntsr1]]

[[Category: Signaling protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Structure of active-like neurotensin receptor==
+<StructureSection load='4xee' size='340' side='right' caption='[[4xee]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-The entry 4xee is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4xee]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XEE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XEE FirstGlance]. <br>
-Authors: Krumm, B.E., White, J.F., Shah, P., Grisshammer, R.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xes|4xes]]</td></tr>
-Description: Structure of active-like neurotensin receptor
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xee OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xee RCSB], [http://www.ebi.ac.uk/pdbsum/4xee PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NTR1_RAT NTR1_RAT]] Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. [[http://www.uniprot.org/uniprot/NEUT_RAT NEUT_RAT]] Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
+__TOC__
+</StructureSection>
+[[Category: Lysozyme]]
+[[Category: Grisshammer, R]]
+[[Category: Krumm, B E]]
 [[Category: Shah, P]]
-[[Category: Krumm, B.E]]
+[[Category: White, J F]]
-[[Category: Grisshammer, R]]
+[[Category: G protein-coupled receptor]]
-[[Category: White, J.F]]
+[[Category: Gpcr]]
+[[Category: Hydrolase]]
+[[Category: Membrane protein]]
+[[Category: Neurotensin receptor]]
+[[Category: Ntsr1]]
+[[Category: Signaling protein]]