4zuo: Difference between revisions
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''' | ==Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor== | ||
<StructureSection load='4zuo' size='340' side='right' caption='[[4zuo]], [[Resolution|resolution]] 1.33Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4zuo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZUO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZUO FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=XS6:6-[(3-AMINOPROPYL)AMINO]-N-HYDROXYHEXANAMIDE'>XS6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zum|4zum]], [[4zun|4zun]], [[4zup|4zup]], [[4zuq|4zuq]], [[4zur|4zur]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zuo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zuo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zuo RCSB], [http://www.ebi.ac.uk/pdbsum/4zuo PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/APHA_MYCRA APHA_MYCRA]] Acts on many types of acetylpolyamines. Has high affinity towards acetylputrescine, acetylcadaverine, acetylspermidine, and acetylspermine. Acts on L-Lys-(epsilon-acetyl)-coumarin, but has very low activity towards acetylated peptides. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Christianson, D W]] | |||
[[Category: Decroos, C]] | [[Category: Decroos, C]] | ||
[[Category: | [[Category: Acetylpolyamine amidohydrolase]] | ||
[[Category: Arginase fold]] | |||
[[Category: Enzyme-inhibitor complex]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Polyamine]] | |||
Revision as of 14:52, 29 July 2015
Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor
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