PLC beta 3 Gq: Difference between revisions

Revision as of 12:46, 1 August 2015 view source Shir Navot (talk \| contribs) 74 edits No edit summary ← Older edit		Revision as of 12:51, 1 August 2015 view source Shir Navot (talk \| contribs) 74 edits No edit summary Newer edit →
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	'''Critical residues in the interface:'''		'''Critical residues in the interface:'''

	The canonical Gα effector-binding region of Gαq, located between α3 and switch 2, is occupied by a helix-turn-helix (Hα1/Hα2) that immediately follows the C2 domain of PLC-β3. <scene name='70/701452/Pro862/3'>Pro862</scene> of PLC-β3 lies within the turn between Hα1 and Hα2, makes extensive contacts with multiple residues of Gαq, and forms the center of a Gαq-binding interface.		The canonical Gα effector-binding region of Gαq, located between α3 and switch 2, is occupied by a helix-turn-helix (Hα1/Hα2) that immediately follows the C2 domain of PLC-β3. <scene name='70/701452/Pro862/4'>Pro862</scene> of PLC-β3 lies within the turn between Hα1 and Hα2, makes extensive contacts with multiple residues of Gαq, and forms the center of a Gαq-binding interface.

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