9ldt: Difference between revisions

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[[Image:9ldt.gif|left|200px]]<br /><applet load="9ldt" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:9ldt.gif|left|200px]]
caption="9ldt, resolution 2.0&Aring;" />
 
'''DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK'''<br />
{{Structure
|PDB= 9ldt |SIZE=350|CAPTION= <scene name='initialview01'>9ldt</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=OXM:OXAMIC ACID'>OXM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27]
|GENE=
}}
 
'''DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
9LDT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ACE:'>ACE</scene>, <scene name='pdbligand=NAD:'>NAD</scene> and <scene name='pdbligand=OXM:'>OXM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LDT OCA].  
9LDT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9LDT OCA].  


==Reference==
==Reference==
Design and synthesis of new enzymes based on the lactate dehydrogenase framework., Dunn CR, Wilks HM, Halsall DJ, Atkinson T, Clarke AR, Muirhead H, Holbrook JJ, Philos Trans R Soc Lond B Biol Sci. 1991 May 29;332(1263):177-84. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1678537 1678537]
Design and synthesis of new enzymes based on the lactate dehydrogenase framework., Dunn CR, Wilks HM, Halsall DJ, Atkinson T, Clarke AR, Muirhead H, Holbrook JJ, Philos Trans R Soc Lond B Biol Sci. 1991 May 29;332(1263):177-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1678537 1678537]
[[Category: L-lactate dehydrogenase]]
[[Category: L-lactate dehydrogenase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: oxidoreductase(choh(d)-nad+(a))]]
[[Category: oxidoreductase(choh(d)-nad+(a))]]


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