4qhu: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal Structure of IL-17A/Fab6785 complex==

~~The entry~~ 4qhu is ~~ON HOLD until Aug 03 2016~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4qhu]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QHU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QHU FirstGlance]. <br>

~~Authors~~: ~~Luo~~, J., ~~Gilliland, G~~.L., ~~Malia, T~~.~~, Obmolova, G~~.~~, Teplyakov, A~~.

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qhu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qhu RCSB], [http://www.ebi.ac.uk/pdbsum/4qhu PDBsum]</span></td></tr>

~~Description~~: ~~Crystal Structure~~ of ~~IL-17A~~/~~Fab6785 complex~~

</table>

[[Category: ~~Unreleased Structures~~]]

== Function ==

[[http://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN]] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

__TOC__

</StructureSection>

[[Category: Gilliland, G L]]

[[Category: Luo, J]]

[[Category: Malia, T]]

[[Category: Obmolova, G]]

~~[[Category: Gilliland, G.L]]~~

[[Category: Teplyakov, A]]

[[Category: ~~Luo, J~~]]

[[Category: Antibody-antigen interaction]]

[[Category: Cystine knot]]

[[Category: Cytokine il-17]]

[[Category: Il-17ra]]

[[Category: Il-17rc]]

[[Category: Immune system]]

[[Category: Molecular asymmetry]]

[[Category: Receptor differentiation]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal Structure of IL-17A/Fab6785 complex==
+<StructureSection load='4qhu' size='340' side='right' caption='[[4qhu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-The entry 4qhu is ON HOLD  until Aug 03 2016
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4qhu]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QHU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QHU FirstGlance]. <br>
-Authors: Luo, J., Gilliland, G.L., Malia, T., Obmolova, G., Teplyakov, A.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qhu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qhu RCSB], [http://www.ebi.ac.uk/pdbsum/4qhu PDBsum]</span></td></tr>
-Description: Crystal Structure of IL-17A/Fab6785 complex
+</table>
-[[Category: Unreleased Structures]]
+== Function ==
+[[http://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN]] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
+__TOC__
+</StructureSection>
+[[Category: Gilliland, G L]]
+[[Category: Luo, J]]
 [[Category: Malia, T]]
 [[Category: Obmolova, G]]
-[[Category: Gilliland, G.L]]
 [[Category: Teplyakov, A]]
-[[Category: Luo, J]]
+[[Category: Antibody-antigen interaction]]
+[[Category: Cystine knot]]
+[[Category: Cytokine il-17]]
+[[Category: Il-17ra]]
+[[Category: Il-17rc]]
+[[Category: Immune system]]
+[[Category: Molecular asymmetry]]
+[[Category: Receptor differentiation]]