5cqj: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of E. coli undecaprenyl pyrophosphate synthase in complex with clomiphene==

~~The entry~~ 5cqj is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5cqj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CQJ OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CQJ FirstGlance].

~~Authors~~: ~~Worrall~~, L.J., ~~Conrady~~, D.G., ~~Strynadka, N~~.C.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=53Q:CLOMIFENE'>53Q</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5cqb|5cqb]]</td></tr>

~~Description:~~

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Ditrans,polycis-undecaprenyl-diphosphate_synthase_((2E,6E)-farnesyl-_diphosphate_specific) Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl- diphosphate specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] </td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cqj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5cqj RCSB], [http://www.ebi.ac.uk/pdbsum/5cqj PDBsum]</td></tr>

[[Category: Conrady, D.G]]

</table>

[[Category: Worrall, L.J]]

== Function ==

[[Category: ~~Strynadka, N.C~~]]

[[http://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI]] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Conrady, D G]]

[[Category: Strynadka, N C]]

[[Category: Worrall, L J]]

[[Category: Antibacterial]]

[[Category: Cell wall]]

[[Category: Transferase]]

[[Category: Transferase-transferase inhibitor complex]]

[[Category: Wall teichoic acid]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of E. coli undecaprenyl pyrophosphate synthase in complex with clomiphene==
+<StructureSection load='5cqj' size='340' side='right' caption='[[5cqj]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
-The entry 5cqj is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5cqj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CQJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CQJ FirstGlance]. <br>
-Authors: Worrall, L.J., Conrady, D.G., Strynadka, N.C.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=53Q:CLOMIFENE'>53Q</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cqb|5cqb]]</td></tr>
-Description:
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ditrans,polycis-undecaprenyl-diphosphate_synthase_((2E,6E)-farnesyl-_diphosphate_specific) Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl- diphosphate specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cqj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5cqj RCSB], [http://www.ebi.ac.uk/pdbsum/5cqj PDBsum]</span></td></tr>
-[[Category: Conrady, D.G]]
+</table>
-[[Category: Worrall, L.J]]
+== Function ==
-[[Category: Strynadka, N.C]]
+[[http://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI]] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Conrady, D G]]
+[[Category: Strynadka, N C]]
+[[Category: Worrall, L J]]
+[[Category: Antibacterial]]
+[[Category: Cell wall]]
+[[Category: Transferase]]
+[[Category: Transferase-transferase inhibitor complex]]
+[[Category: Wall teichoic acid]]