4wq2: Difference between revisions
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''' | ==Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound== | ||
<StructureSection load='4wq2' size='340' side='right' caption='[[4wq2]], [[Resolution|resolution]] 1.64Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4wq2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQ2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3SU:(2Z)-3-(6-BROMO-1H-INDOL-3-YL)-2-SULFANYLPROP-2-ENOIC+ACID'>3SU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wq2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wq2 RCSB], [http://www.ebi.ac.uk/pdbsum/4wq2 PDBsum]</span></td></tr> | |||
</table> | |||
[[ | == Function == | ||
[[ | [[http://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN]] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | ||
[[Category: | __TOC__ | ||
[[Category: Allemann, R | </StructureSection> | ||
[[Category: Hallett, M | [[Category: Adams, S E]] | ||
[[Category: | [[Category: Allemann, R K]] | ||
[[Category: Hallett, M B]] | |||
[[Category: Miller, D J]] | |||
[[Category: Rizkallah, P J]] | |||
[[Category: Calcium binding]] | |||
[[Category: Calpain]] | |||
[[Category: Domain vi]] | |||
[[Category: Ef-hand]] | |||
[[Category: Human]] | |||
[[Category: Hydrolase]] | |||
[[Category: Protease]] | |||
Revision as of 12:30, 2 September 2015
Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound
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