4wq3: Difference between revisions
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==Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-bromoindol-3-yl)acrylic acid) bound== | |||
<StructureSection load='4wq3' size='340' side='right' caption='[[4wq3]], [[Resolution|resolution]] 1.79Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4wq3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQ3 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3SU:(2Z)-3-(6-BROMO-1H-INDOL-3-YL)-2-SULFANYLPROP-2-ENOIC+ACID'>3SU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wq3 RCSB], [http://www.ebi.ac.uk/pdbsum/4wq3 PDBsum]</span></td></tr> | |||
</table> | |||
[[ | == Function == | ||
[[ | [[http://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN]] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. | ||
[[ | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Allemann, R | [[Category: Adams, S E]] | ||
[[Category: Hallett, M | [[Category: Allemann, R K]] | ||
[[Category: | [[Category: Hallett, M B]] | ||
[[Category: Miller, D J]] | |||
[[Category: Rizkallah, P J]] | |||
[[Category: Robinson, E J]] | |||
[[Category: Calcium binding domain]] | |||
[[Category: Cysteine protease]] | |||
[[Category: Domain vi]] | |||
[[Category: Hydrolase]] | |||
[[Category: Mercaptoacrylic acid]] | |||
Revision as of 12:30, 2 September 2015
Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-bromoindol-3-yl)acrylic acid) bound
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