5bxp: Difference between revisions

Line 1:

'''~~Unreleased~~ structure'''

==LNBase in complex with LNB-LOGNAc==

== Structural highlights ==

<table><tr><td colspan='2'>[[5bxp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BXP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BXP FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=LOG:LOGNAC'>LOG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bxr|5bxr]], [[5bxt|5bxt]], [[5bxs|5bxs]]</td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lacto-N-biosidase Lacto-N-biosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.140 3.2.1.140] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bxp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bxp RCSB], [http://www.ebi.ac.uk/pdbsum/5bxp PDBsum]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

The synthesis of potent inhibitors for lacto-N-biosidases and X-ray structural characterization of these compounds in complex with BbLNBase is described.

~~The entry 5bxp is ON HOLD until Paper Publication~~

Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis.,Hattie M, Ito T, Debowski AW, Arakawa T, Katayama T, Yamamoto K, Fushinobu S, Stubbs KA Chem Commun (Camb). 2015 Aug 27. PMID:26312778<ref>PMID:26312778</ref>

~~Authors: Ito~~, T.~~, Arakawa, T~~.~~, Fushinobu, S~~.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~Description~~:

== References ==

[[Category: ~~Unreleased Structures~~]]

__TOC__

</StructureSection>

[[Category: Lacto-N-biosidase]]

[[Category: Arakawa, T]]

[[Category: Fushinobu, S]]

[[Category: Ito, T]]

[[Category: ~~Arakawa, T~~]]

[[Category: Distal gut]]

[[Category: Human milk oligosaccharide]]

[[Category: Hydrolase]]

[[Category: Inhibitor]]

[[Category: Tim barrel]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==LNBase in complex with LNB-LOGNAc==
+<StructureSection load='5bxp' size='340' side='right' caption='[[5bxp]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5bxp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BXP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BXP FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=LOG:LOGNAC'>LOG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bxr|5bxr]], [[5bxt|5bxt]], [[5bxs|5bxs]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lacto-N-biosidase Lacto-N-biosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.140 3.2.1.140] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bxp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bxp RCSB], [http://www.ebi.ac.uk/pdbsum/5bxp PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The synthesis of potent inhibitors for lacto-N-biosidases and X-ray structural characterization of these compounds in complex with BbLNBase is described.
-The entry 5bxp is ON HOLD  until Paper Publication
+Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis.,Hattie M, Ito T, Debowski AW, Arakawa T, Katayama T, Yamamoto K, Fushinobu S, Stubbs KA Chem Commun (Camb). 2015 Aug 27. PMID:26312778<ref>PMID:26312778</ref>
-Authors: Ito, T., Arakawa, T., Fushinobu, S.
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-Description:
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Lacto-N-biosidase]]
+[[Category: Arakawa, T]]
 [[Category: Fushinobu, S]]
 [[Category: Ito, T]]
-[[Category: Arakawa, T]]
+[[Category: Distal gut]]
+[[Category: Human milk oligosaccharide]]
+[[Category: Hydrolase]]
+[[Category: Inhibitor]]
+[[Category: Tim barrel]]