4wif: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of E47Q mutant cytidine deaminase from Mycobacterium tuberculosis (MtCDA E47Q)==

~~The entry~~ 4wif is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4wif]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WIF OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WIF FirstGlance].

~~Authors~~: ~~Trivella~~, D.B.~~, Sanchez~~-~~Quitian~~, A.Z., ~~Basso, L~~.A., ~~Santos, D~~.S.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4wig|4wig]]</td></tr>

~~Description~~: ~~Crystal structure~~ of ~~E47Q mutant~~ cytidine ~~deaminase from Mycobacterium tuberculosis~~ (~~MtCDA E47Q~~)

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Cytidine_deaminase Cytidine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.5 3.5.4.5] </td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wif OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wif RCSB], [http://www.ebi.ac.uk/pdbsum/4wif PDBsum]</td></tr>

[[Category: Sanchez-Quitian, A.Z]]

</table>

[[Category: Trivella, D.B]]

== Function ==

[[Category: ~~Basso, L.A~~]]

[[http://www.uniprot.org/uniprot/CDD_MYCTO CDD_MYCTO]] Recycles cytidine and 2-deoxycytidine for uridine and 2-deoxyuridine synthesis, respectively. Catalyzes the hydrolytic deamination of cytidine and 2-deoxycytidine to form, respectively, uridine and 2-deoxyuridine (By similarity).

[[Category: ~~Santos, D.S~~]]

__TOC__

</StructureSection>

[[Category: Cytidine deaminase]]

[[Category: Basso, L A]]

[[Category: Sanchez-Quitian, A Z]]

[[Category: Santos, D S]]

[[Category: Trivella, D B]]

[[Category: Hydrolase]]

[[Category: Mtcda e47q]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of E47Q mutant cytidine deaminase from Mycobacterium tuberculosis (MtCDA E47Q)==
+<StructureSection load='4wif' size='340' side='right' caption='[[4wif]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-The entry 4wif is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4wif]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WIF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WIF FirstGlance]. <br>
-Authors: Trivella, D.B., Sanchez-Quitian, A.Z., Basso, L.A., Santos, D.S.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wig|4wig]]</td></tr>
-Description: Crystal structure of E47Q mutant cytidine deaminase from Mycobacterium tuberculosis (MtCDA E47Q)
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytidine_deaminase Cytidine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.5 3.5.4.5] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wif OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wif RCSB], [http://www.ebi.ac.uk/pdbsum/4wif PDBsum]</span></td></tr>
-[[Category: Sanchez-Quitian, A.Z]]
+</table>
-[[Category: Trivella, D.B]]
+== Function ==
-[[Category: Basso, L.A]]
+[[http://www.uniprot.org/uniprot/CDD_MYCTO CDD_MYCTO]] Recycles cytidine and 2-deoxycytidine for uridine and 2-deoxyuridine synthesis, respectively. Catalyzes the hydrolytic deamination of cytidine and 2-deoxycytidine to form, respectively, uridine and 2-deoxyuridine (By similarity).
-[[Category: Santos, D.S]]
+__TOC__
+</StructureSection>
+[[Category: Cytidine deaminase]]
+[[Category: Basso, L A]]
+[[Category: Sanchez-Quitian, A Z]]
+[[Category: Santos, D S]]
+[[Category: Trivella, D B]]
+[[Category: Hydrolase]]
+[[Category: Mtcda e47q]]