4xj7: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal Structure of E112A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium soaked with AMP==

~~The entry~~ 4xj7 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4xj7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJ7 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJ7 FirstGlance].

~~Authors~~: ~~Mathiharan~~, Y.K., ~~Murthy~~, M.R.N.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4ryt|4ryt]], [[4ryu|4ryu]]</td></tr>

~~Description~~: ~~Crystal Structure~~ of ~~E112A Mutant~~ of ~~Stationary Phase Survival Protein~~ (~~SurE~~) ~~from Salmonella typhimurium soaked with AMP~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xj7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xj7 RCSB], [http://www.ebi.ac.uk/pdbsum/4xj7 PDBsum]</td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

[[Category: Murthy, M.R.N]]

== Function ==

[[Category: ~~Mathiharan, Y.K~~]]

[[http://www.uniprot.org/uniprot/SURE_SALTY SURE_SALTY]] Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.[HAMAP-Rule:MF_00060]

__TOC__

</StructureSection>

[[Category: Mathiharan, Y K]]

[[Category: Murthy, M R.N]]

[[Category: Domain swapping]]

[[Category: Hydrolase]]

[[Category: Phosphatase]]

[[Category: Rossmann fold like]]

[[Category: Stationary phase survival protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal Structure of E112A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium soaked with AMP==
+<StructureSection load='4xj7' size='340' side='right' caption='[[4xj7]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-The entry 4xj7 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4xj7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJ7 FirstGlance]. <br>
-Authors: Mathiharan, Y.K., Murthy, M.R.N.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ryt|4ryt]], [[4ryu|4ryu]]</td></tr>
-Description: Crystal Structure of E112A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium soaked with AMP
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xj7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xj7 RCSB], [http://www.ebi.ac.uk/pdbsum/4xj7 PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Murthy, M.R.N]]
+== Function ==
-[[Category: Mathiharan, Y.K]]
+[[http://www.uniprot.org/uniprot/SURE_SALTY SURE_SALTY]] Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.[HAMAP-Rule:MF_00060]
+__TOC__
+</StructureSection>
+[[Category: Mathiharan, Y K]]
+[[Category: Murthy, M R.N]]
+[[Category: Domain swapping]]
+[[Category: Hydrolase]]
+[[Category: Phosphatase]]
+[[Category: Rossmann fold like]]
+[[Category: Stationary phase survival protein]]