2igx: Difference between revisions

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|PDB= 2igx |SIZE=350|CAPTION= <scene name='initialview01'>2igx</scene>, resolution 1.70&Aring;
|PDB= 2igx |SIZE=350|CAPTION= <scene name='initialview01'>2igx</scene>, resolution 1.70&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=A1T:5-PENTYL-N-{[4'-(PIPERIDIN-1-YLCARBONYL)BIPHENYL-4-YL]METHYL}-N-[1-(PYRIDIN-2-YLMETHYL)PIPERIDIN-4-YL]PYRIDINE-2-CARBOXAMIDE'>A1T</scene>
|LIGAND= <scene name='pdbligand=A1T:5-PENTYL-N-{[4&#39;-(PIPERIDIN-1-YLCARBONYL)BIPHENYL-4-YL]METHYL}-N-[1-(PYRIDIN-2-YLMETHYL)PIPERIDIN-4-YL]PYRIDINE-2-CARBOXAMIDE'>A1T</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39]  
|ACTIVITY= [http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39]  
|GENE=  
|GENE=  
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[[Category: achiral inhibitor]]
[[Category: achiral inhibitor]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:29:33 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:20:45 2008''

Revision as of 13:20, 23 March 2008

File:2igx.gif


Drag the structure with the mouse to rotate
2igx, resolution 1.70Å
Ligands: A1T
Activity: Plasmepsin II, with EC number 3.4.23.39
Coordinates: save as pdb, mmCIF, xml



Achiral, Cheap and Potent Inhibitors of Plasmepsins II


About this Structure

2IGX is a Single protein structure of sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

Achiral, cheap, and potent inhibitors of Plasmepsins I, II, and IV., Boss C, Corminboeuf O, Grisostomi C, Meyer S, Jones AF, Prade L, Binkert C, Fischli W, Weller T, Bur D, ChemMedChem. 2006 Dec;1(12):1341-5. PMID:17091526

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