2qjg: Difference between revisions

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<StructureSection load='2qjg' size='340' side='right' caption='[[2qjg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='2qjg' size='340' side='right' caption='[[2qjg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2qjg]] is a 20 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QJG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QJG FirstGlance]. <br>
<table><tr><td colspan='2'>[[2qjg]] is a 20 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QJG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QJG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F2P:1,6-DI-O-PHOSPHONO-D-ALLITOL'>F2P</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F2P:1,6-DI-O-PHOSPHONO-D-ALLITOL'>F2P</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qjh|2qjh]], [[2qji|2qji]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qjh|2qjh]], [[2qji|2qji]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qjg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qjg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qjg RCSB], [http://www.ebi.ac.uk/pdbsum/2qjg PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qjg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qjg OCA], [http://pdbe.org/2qjg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qjg RCSB], [http://www.ebi.ac.uk/pdbsum/2qjg PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Y400_METJA Y400_METJA]] Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. Can also catalyze the cleavage of fructose-1,6-bisphosphate (FBP) to glyceraldehyde-3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP).<ref>PMID:15182204</ref> <ref>PMID:18318840</ref>   
[[http://www.uniprot.org/uniprot/ADHS_METJA ADHS_METJA]] Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. Can also catalyze the cleavage of fructose-1,6-bisphosphate (FBP) to glyceraldehyde-3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP).[HAMAP-Rule:MF_00960]<ref>PMID:15182204</ref> <ref>PMID:18318840</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2qjg" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Methanocaldococcus jannaschii]]
[[Category: Atcc 43067]]
[[Category: Ealick, S E]]
[[Category: Ealick, S E]]
[[Category: Morar, M]]
[[Category: Morar, M]]
[[Category: Beta-alpha barrel]]
[[Category: Beta-alpha barrel]]
[[Category: Lyase]]
[[Category: Lyase]]