1bf0: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[1bf0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Dendroaspis_angusticeps Dendroaspis angusticeps~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BF0 FirstGlance]. <br>

<table><tr><td colspan='2'>[[1bf0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Denan Denan]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BF0 FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bf0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bf0 RCSB], [http://www.ebi.ac.uk/pdbsum/1bf0 PDBsum]</span></td></tr>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bf0 OCA], [http://pdbe.org/1bf0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bf0 RCSB], [http://www.ebi.ac.uk/pdbsum/1bf0 PDBsum]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/~~TXCA_DENAN TXCA_DENAN~~]] Potent blocker of high-voltage-activated calcium ion channels in the nanomolar range, particularly the L-type channels in cerebellar granule cells. The sensitivity of L-, N- and P-type channels to CAC is tissue and species-dependent. Blocks the L-type current of cardiac cells, depressing cardiac contractility.

[[http://www.uniprot.org/uniprot/VKTHC_DENAN VKTHC_DENAN]] Potent blocker of high-voltage-activated calcium ion channels in the nanomolar range, particularly the L-type channels in cerebellar granule cells. The sensitivity of L-, N- and P-type channels to CAC is tissue and species-dependent. Blocks the L-type current of cardiac cells, depressing cardiac contractility.

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

== References ==

__TOC__

</StructureSection>

[[Category: ~~Dendroaspis angusticeps~~]]

[[Category: Denan]]

[[Category: Desne, F]]

[[Category: Gilquin, B]]

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 <StructureSection load='1bf0' size='340' side='right' caption='[[1bf0]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1bf0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dendroaspis_angusticeps Dendroaspis angusticeps]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BF0 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1bf0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Denan Denan]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BF0 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bf0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bf0 RCSB], [http://www.ebi.ac.uk/pdbsum/1bf0 PDBsum]</span></td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bf0 OCA], [http://pdbe.org/1bf0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bf0 RCSB], [http://www.ebi.ac.uk/pdbsum/1bf0 PDBsum]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/TXCA_DENAN TXCA_DENAN]] Potent blocker of high-voltage-activated calcium ion channels in the nanomolar range, particularly the L-type channels in cerebellar granule cells. The sensitivity of L-, N- and P-type channels to CAC is tissue and species-dependent. Blocks the L-type current of cardiac cells, depressing cardiac contractility.
+[[http://www.uniprot.org/uniprot/VKTHC_DENAN VKTHC_DENAN]] Potent blocker of high-voltage-activated calcium ion channels in the nanomolar range, particularly the L-type channels in cerebellar granule cells. The sensitivity of L-, N- and P-type channels to CAC is tissue and species-dependent. Blocks the L-type current of cardiac cells, depressing cardiac contractility.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 25: / Line 25: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 1bf0" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Dendroaspis angusticeps]]
+[[Category: Denan]]
 [[Category: Desne, F]]
 [[Category: Gilquin, B]]