1tck: Difference between revisions
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<StructureSection load='1tck' size='340' side='right' caption='[[1tck]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | <StructureSection load='1tck' size='340' side='right' caption='[[1tck]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1tck]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1tck]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Conge Conge]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TCK FirstGlance]. <br> | ||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tch|1tch]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tch|1tch]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tck OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tck RCSB], [http://www.ebi.ac.uk/pdbsum/1tck PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tck OCA], [http://pdbe.org/1tck PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tck RCSB], [http://www.ebi.ac.uk/pdbsum/1tck PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/ | [[http://www.uniprot.org/uniprot/CM3A_CONGE CM3A_CONGE]] Mu-conotoxins block voltage-gated sodium channels (Nav). This toxin potently blocks Nav1.4/SCN4A. It also moderately blocks rNav1.1/SCN1A, rNav1.2/SCN2A, and mNav1.6/SCN8A. The inhibition is reversible. Induces paralysis in vertebrates.<ref>PMID:18950653</ref> <ref>PMID:21652775</ref> <ref>PMID:2410412</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 1tck" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Conge]] | ||
[[Category: Inagaki, F]] | [[Category: Inagaki, F]] | ||
[[Category: Kohda, D]] | [[Category: Kohda, D]] | ||
[[Category: Lancelin, J M]] | [[Category: Lancelin, J M]] | ||
[[Category: Neurotoxin]] | [[Category: Neurotoxin]] | ||
