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| ==Crystal structure of human Mitochondrial Transcription Termination Factor 3==
| | REMOVED: The PDB entry 3opg was removed. |
| <StructureSection load='3opg' size='340' side='right' caption='[[3opg]], [[Resolution|resolution]] 2.71Å' scene=''>
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| == Structural highlights ==
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| <table><tr><td colspan='2'>[[3opg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3my3 3my3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OPG FirstGlance]. <br>
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| </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CGI-12, MTERFD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3opg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3opg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3opg RCSB], [http://www.ebi.ac.uk/pdbsum/3opg PDBsum]</span></td></tr>
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| </table>
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| == Function ==
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| [[http://www.uniprot.org/uniprot/MTER1_HUMAN MTER1_HUMAN]] Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).<ref>PMID:17662942</ref>
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| == Evolutionary Conservation ==
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| [[Image:Consurf_key_small.gif|200px|right]]
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| Check<jmol>
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| <jmolCheckbox>
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| <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/3opg_consurf.spt"</scriptWhenChecked>
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| <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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| <text>to colour the structure by Evolutionary Conservation</text>
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| </jmolCheckbox>
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| </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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| <div style="clear:both"></div>
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| == References ==
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| <references/>
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| __TOC__
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| </StructureSection>
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| [[Category: Homo sapiens]]
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| [[Category: Cho, H S]]
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| [[Category: Cho, S G]]
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| [[Category: Kim, D U]]
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| [[Category: Mterf3]]
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| [[Category: Transcription]]
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