4zd5: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
''' | ==Catalytic domain of Sst2 F403A mutant== | ||
<StructureSection load='4zd5' size='340' side='right' caption='[[4zd5]], [[Resolution|resolution]] 2.07Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4zd5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZD5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZD5 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jxe|4jxe]], [[4ms7|4ms7]], [[4msj|4msj]], [[3rzu|3rzu]], [[2znr|2znr]], [[4zd4|4zd4]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zd5 OCA], [http://pdbe.org/4zd5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zd5 RCSB], [http://www.ebi.ac.uk/pdbsum/4zd5 PDBsum]</span></td></tr> | |||
[[ | </table> | ||
[[Category: Shrestha, R | == Function == | ||
[[http://www.uniprot.org/uniprot/SST2_SCHPO SST2_SCHPO]] Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in the multivesicular body (MVB) sorting pathway. Required for ubiquitin-dependent sorting of proteins into the endosome and subsequent trafficking to the vacuole. May regulate MVB sorting through deubiquitination of ubiquitinated ESCRT proteins.<ref>PMID:17660439</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Shrestha, R K]] | |||
[[Category: Helix-beta-helix sandwich zinc metalloprotease endosome ubiquitin]] | |||
[[Category: Hydrolase]] | |||
Revision as of 04:05, 16 October 2015
Catalytic domain of Sst2 F403A mutant
| ||||||||||||
