5d98: Difference between revisions

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'''Unreleased structure'''
==Influenza C Virus RNA-dependent RNA Polymerase - Space group P43212==
 
<StructureSection load='5d98' size='340' side='right' caption='[[5d98]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
The entry 5d98 is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5d98]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D98 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D98 FirstGlance]. <br>
Authors: Hengrung, N., El Omari, K., Serna Martin, I., Vreede, F.T., Cusack, S., Rambo, R.P., Vonrhein, C., Bricogne, G., Stuart, D.I., Grimes, J.M., Fodor, E.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5d9a|5d9a]]</td></tr>
Description:  
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d98 OCA], [http://pdbe.org/5d98 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d98 RCSB], [http://www.ebi.ac.uk/pdbsum/5d98 PDBsum]</span></td></tr>
[[Category: Fodor, E]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PA_INCJH PA_INCJH]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity). [[http://www.uniprot.org/uniprot/PB2_INCJH PB2_INCJH]] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1 (By similarity). [[http://www.uniprot.org/uniprot/RDRP_INCJH RDRP_INCJH]] RNA-dependent RNA polymerase which is responsible for replication and transcription of virus segments. Binds the promoter sequence of the encapsidated viral RNA. Displays an endonuclease activity involved in cap-stealing. Cleaves cellular pre-mRNA to generate primers for viral transcription (By similarity).
__TOC__
</StructureSection>
[[Category: RNA-directed RNA polymerase]]
[[Category: Bricogne, G]]
[[Category: Bricogne, G]]
[[Category: Cusack, S]]
[[Category: Cusack, S]]
[[Category: El Omari, K]]
[[Category: Fodor, E]]
[[Category: Vreede, F.T]]
[[Category: Grimes, J M]]
[[Category: Grimes, J.M]]
[[Category: Hengrung, N]]
[[Category: Martin, I Serna]]
[[Category: Omari, K El]]
[[Category: Rambo, R P]]
[[Category: Stuart, D I]]
[[Category: Vonrhein, C]]
[[Category: Vonrhein, C]]
[[Category: Hengrung, N]]
[[Category: Vreede, F T]]
[[Category: Rambo, R.P]]
[[Category: Influenza]]
[[Category: Stuart, D.I]]
[[Category: Influenza c virus]]
[[Category: Serna Martin, I]]
[[Category: Negative-strand virus]]
[[Category: Rna-dependent rna polymerase]]
[[Category: Transferase-rna complex]]
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