Cluster of Differentiation CD38: Difference between revisions
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{{STRUCTURE_3gc6| PDB=3gc6 | SIZE=400| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Glycosylated Cluster of Differentiation 38 (CD38) complex with sulfate [[3gc6]] }} | {{STRUCTURE_3gc6| PDB=3gc6 | SIZE=400| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Glycosylated Cluster of Differentiation 38 (CD38) complex with sulfate [[3gc6]] }} | ||
[[Cluster of Differentiation 38]] (CD38), known also as ''ADP-ribosyl cyclase 1'' (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling. '''ADP-ribosyl cyclase''' (ADPRC) is the ''Aplysia californica'' homolog of CD38. It catalyzes the synthesis and hydrolysis of cyclic ADP-ribose. It uses NAD+ as substrate and produces cyclic ADP-ribose (cADPR). | [[Cluster of Differentiation 38]] (CD38), known also as '''ADP-ribosyl cyclase 1''' (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR). It is found on the surface of immune cells. It also functions in cell adhesion, signal transduction and Ca++ signaling. '''ADP-ribosyl cyclase''' (ADPRC) is the ''Aplysia californica'' homolog of CD38. It catalyzes the synthesis and hydrolysis of cyclic ADP-ribose. It uses NAD+ as substrate and produces cyclic ADP-ribose (cADPR). | ||
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