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====October: B<sub>12</sub> photoreceptor in bacteria regulates transcription==== | ====October: B<sub>12</sub> photoreceptor in bacteria regulates transcription==== | ||
<ref group="xtra">PMID: 26416754</ref><references group="xtra"/> | <ref group="xtra">PMID: 26416754</ref><references group="xtra"/> | ||
:*CarH photoreceptors bind DNA on their N-terminal domains, and adenosylcobalamin (a vitamin B<sub>12</sub> derivitave) between their middle and C-terminal domains. | :*CarH photoreceptors bind DNA on their N-terminal domains, and adenosylcobalamin (a vitamin B<sub>12</sub> derivitave) between their middle and C-terminal domains ([[5c8e]]). The DNA-binding conformation is a homo-tetramer. | ||
:*Light breaks a Co-C bond, releasing 5'-deoxyadenosine, causing a domain orientation shift of >8 Å. This disrupts | |||
:*Extended data has static figures only (no movies). | |||
===2012=== | ===2012=== | ||
====April: Molecular Juggling of B12 in Methyltransferase==== | ====April: Molecular Juggling of B12 in Methyltransferase==== | ||
