Avidin: Difference between revisions

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<applet load='2avi' size='300' frame='true' align='right' caption='Two monomers of the avidin tetramer complex with biotin (PDB code [[2avi]])' />
<applet load='2avi' size='300' frame='true' align='right' caption='Two monomers of the avidin tetramer complex with biotin (PDB code [[2avi]])' />


[[Avidin]] '''(Av)''' is a protein found in egg white which binds biotin (vitamin B7) with high affinity.  This property makes it a powerful tool in various protein pull-down assays.  Similar proteins are streptavidin (StrAv) from the bacterium ''Streptomyces avidinii'', Rhizavidin (RhiAv) from ''Rhizobium etli'', Xenavidin from frog, and the avidin-related proteins AVR2 and AVR4.  The N-acetylglucosamine sugars are shown as space filling objects in the image on the left.
[[Avidin]] '''(Av)''' is a protein found in egg white which binds biotin (vitamin B7) with high affinity.  This property makes it a powerful tool in various protein pull-down assays.  Similar proteins are:<br />
* '''Streptavidin''' (StrAv) from the bacterium ''Streptomyces avidinii''<br />
* '''Rhizavidin''' (RhiAv) from ''Rhizobium etli''<br />
* '''Xenavidin''' from frog<br />
* '''Tamavidin''' from fungi<br />
* '''Bradavidin''' from ''Bradyrhizobium japonicum''<br />
* '''Hoefavidin''' from ''Hoeflea phototrophica''<br />
* '''Shwanavidin''' from ''Shewanella dentrifica''<br />
* '''AVR2''' and '''AVR4''' are avidin-related proteins.


Avidin is one of the [[CBI Molecules]] being studied in the  [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].
Avidin is one of the [[CBI Molecules]] being studied in the  [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].