Avidin: Difference between revisions
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<applet load='2avi' size='300' frame='true' align='right' caption='Two monomers of the avidin tetramer complex with biotin (PDB code [[2avi]])' /> | <applet load='2avi' size='300' frame='true' align='right' caption='Two monomers of the avidin tetramer complex with biotin (PDB code [[2avi]])' /> | ||
[[Avidin]] '''(Av)''' is a protein found in egg white which binds biotin (vitamin B7) with high affinity. This property makes it a powerful tool in various protein pull-down assays. Similar proteins are | [[Avidin]] '''(Av)''' is a protein found in egg white which binds biotin (vitamin B7) with high affinity. This property makes it a powerful tool in various protein pull-down assays. Similar proteins are:<br /> | ||
* '''Streptavidin''' (StrAv) from the bacterium ''Streptomyces avidinii''<br /> | |||
* '''Rhizavidin''' (RhiAv) from ''Rhizobium etli''<br /> | |||
* '''Xenavidin''' from frog<br /> | |||
* '''Tamavidin''' from fungi<br /> | |||
* '''Bradavidin''' from ''Bradyrhizobium japonicum''<br /> | |||
* '''Hoefavidin''' from ''Hoeflea phototrophica''<br /> | |||
* '''Shwanavidin''' from ''Shewanella dentrifica''<br /> | |||
* '''AVR2''' and '''AVR4''' are avidin-related proteins. | |||
Avidin is one of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground]. | Avidin is one of the [[CBI Molecules]] being studied in the [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground]. | ||