Barnase: Difference between revisions
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{{STRUCTURE_1bni| PDB=1bni | SIZE=400| SCENE=Barnase/Cv/1 |right|CAPTION='3 monomers of barnase [[1bni]]' }} | {{STRUCTURE_1bni| PDB=1bni | SIZE=400| SCENE=Barnase/Cv/1 |right|CAPTION='3 monomers of barnase [[1bni]]' }} | ||
<StructureSection load='1brn' size='450' side='right' scene= caption='Lymnaea acetylcholine-binding protein pentamer complex with acetylcholine (PDB code 3wip)'> | |||
== Function == | |||
'''Barnase''' (BA, BActerial RiboNucleASE) is a bacterial ribonuclease synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA. | '''Barnase''' (BA, BActerial RiboNucleASE) is a bacterial ribonuclease synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA. | ||
== Relevance == | |||
BA structure was used extensively for studying protein folding. | |||
== Structural highlights == | |||
BA hydrolyzes RNA at GpN sites where the positively charge Lys and Arg coordinate the RNA phosphate group. | |||
== 3D Structures of Barnase == | == 3D Structures of Barnase == | ||
Revision as of 08:57, 9 November 2015
Template:STRUCTURE 1bni <StructureSection load='1brn' size='450' side='right' scene= caption='Lymnaea acetylcholine-binding protein pentamer complex with acetylcholine (PDB code 3wip)'>
Function
Barnase (BA, BActerial RiboNucleASE) is a bacterial ribonuclease synthesized and secreted by the bacterium Bacillus amyloliquefaciens. The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA.
Relevance
BA structure was used extensively for studying protein folding.
Structural highlights
BA hydrolyzes RNA at GpN sites where the positively charge Lys and Arg coordinate the RNA phosphate group.
3D Structures of Barnase
Updated on 09-November-2015
