Sandbox8999: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 20: | Line 20: | ||
'''Endocytosis''' | '''Endocytosis''' | ||
The formation of most cellular vesicles are facilitated by coat-proteins like clathrin.<ref name ="johnson"> Johnson, G. T., & Goodsell, D. (2007). Molecule of the Month: Clathrin. [http://dx.doi.org/10.2210/rcsb_pdb/mom_2007_4 doi: 10.2210/rcsb_pdb/mom_2007_4]</ref> Endocytic events are initiated through the activity of the clathrin coat and adaptor proteins that select the “cargo” that will be carried into the cell in vesicles.10 Cells endocytose vesicles from the plasma membrane to perform housekeeping tasks such as taking up nutrients, importing signaling receptors, mediating immune responses, cleaning up cell debris, or providing a pathway for pathogens or toxins.<ref name="johnson" /> | The formation of most cellular vesicles are facilitated by coat-proteins like clathrin.<ref name ="johnson"> Johnson, G. T., & Goodsell, D. (2007). Molecule of the Month: Clathrin. [http://dx.doi.org/10.2210/rcsb_pdb/mom_2007_4 doi: 10.2210/rcsb_pdb/mom_2007_4]</ref> Endocytic events are initiated through the activity of the clathrin coat and adaptor proteins that select the “cargo” that will be carried into the cell in vesicles.<ref name="mcpherson"> McPherson, P. S., Ritter, B., & Wendland, B. Clathrin-Mediated Endocytosis. (2009). Clathrin-Mediated Endocytosis. In Trafficking Inside Cells: Pathways, Mechanisms, and Regulation (Section II). [http://dx.doi.org/10.1007/978-0-387-93877-6_9 doi: 10.1007/978-0-387-93877-6_9]</ref> Cells endocytose vesicles from the plasma membrane to perform housekeeping tasks such as taking up nutrients, importing signaling receptors, mediating immune responses, cleaning up cell debris, or providing a pathway for pathogens or toxins.<ref name="johnson" /> | ||
'''The Canonical and Noncanonical Pathway''' | '''The Canonical and Noncanonical Pathway''' | ||
