GABA receptor: Difference between revisions

Line 1:

<Structure load='<Structure load='Insert PDB code or filename here' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /><Structure load='4MQE' size='350' frame='true' align='right' caption='Figure 1. Display of the GABAB receptor while in the unbound state (Geng, 2013)' scene='Insert optional scene name here' />

GABA (i.e. gamma-aminobutyric acid) is the primary inhibitory neurotransmitter of the vertebrate central nervous system (Kerr, 1995). GABA can bind one of two different receptor proteins, each using a discrete mechanism to elicit a cellular response. Upon binding with GABA, GABAB receptors utilize a second messenger amplification pathway that ultimately results in an inhibitory signal for neuronal transmission. This pathway for signal transmission differs from GABAA receptors, which are considered ligand-gated ion channels as the binding of GABA results in the opening of ion channels leading to the inhibition of a neuronal signal.

GABA receptor: Difference between revisions

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

Revision as of 03:26, 16 November 2015 view source Jonathan Hurst (talk \| contribs) 41 edits No edit summary ← Older edit		Revision as of 22:15, 16 November 2015 view source Patrick Farrell (talk \| contribs) 4 edits No edit summary Newer edit →
Line 1:		Line 1:
	<Structure load='4MQE' size='350' frame='true' align='right' caption='Figure 1. Display of the GABAB receptor while in the unbound state (Geng, 2013)' scene='Insert optional scene name here' />		<Structure load='<Structure load='Insert PDB code or filename here' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' />' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /><Structure load='4MQE' size='350' frame='true' align='right' caption='Figure 1. Display of the GABAB receptor while in the unbound state (Geng, 2013)' scene='Insert optional scene name here' />
	GABA (i.e. gamma-aminobutyric acid) is the primary inhibitory neurotransmitter of the vertebrate central nervous system (Kerr, 1995). GABA can bind one of two different receptor proteins, each using a discrete mechanism to elicit a cellular response. Upon binding with GABA, GABAB receptors utilize a second messenger amplification pathway that ultimately results in an inhibitory signal for neuronal transmission. This pathway for signal transmission differs from GABAA receptors, which are considered ligand-gated ion channels as the binding of GABA results in the opening of ion channels leading to the inhibition of a neuronal signal.		GABA (i.e. gamma-aminobutyric acid) is the primary inhibitory neurotransmitter of the vertebrate central nervous system (Kerr, 1995). GABA can bind one of two different receptor proteins, each using a discrete mechanism to elicit a cellular response. Upon binding with GABA, GABAB receptors utilize a second messenger amplification pathway that ultimately results in an inhibitory signal for neuronal transmission. This pathway for signal transmission differs from GABAA receptors, which are considered ligand-gated ion channels as the binding of GABA results in the opening of ion channels leading to the inhibition of a neuronal signal.