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| == Structural highlights == | | == Structural highlights == |
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| <scene name='47/473540/Cv/2'>The GTP binding site</scene>. | | <scene name='47/473540/Cv/2'>The GTP binding site</scene> (PDB code [[1w5b]]).<ref>PMID:15558053</ref> |
| </StructureSection> | | </StructureSection> |
| == 3D Structures of cell division protein Ftsz == | | == 3D Structures of cell division protein Ftsz == |
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| **[[4m8i]] - Ftsz + GDP – ''Staphylococcus epidermidis''<br /> | | **[[4m8i]] - Ftsz + GDP – ''Staphylococcus epidermidis''<br /> |
| }} | | }} |
| | | == References == |
| | <references/> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |
Revision as of 09:21, 30 November 2015
| Function
Cell Division Protein FtsZ (Ftsz) is the prokaryotic homolog of tubulin. Ftsz assembles into a ring at the site of the septum in bacterial cell division. Ftsz stands for Filamenting Temperature-Sensitive mutant Z. Ftsz can bind GTP and hydrolyze it to GDP.
Structural highlights
The GTP binding site (PDB code 1w5b).[1]
- ↑ Oliva MA, Cordell SC, Lowe J. Structural insights into FtsZ protofilament formation. Nat Struct Mol Biol. 2004 Dec;11(12):1243-50. Epub 2004 Nov 21. PMID:15558053 doi:10.1038/nsmb855
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3D Structures of cell division protein Ftsz
Updated on 30-November-2015
{"openlevels":0}
- Ftsz
- 1w5b – AaFtsz – Aquifex aeolicus
- 2vam, 2vxy – BsFtsz – Bacillus subtilis
- 1w59, 1w5a, 1fsz – MjFtsz – Methanocaldococcus janaschii
- 1w5e - MjFtsz (mutant)
- 1w5f – Ftsz (mutant) – Thermotoga maritima
- 3vo9, 3vpa - SaFtsz – Staphylococcus aureus
- 3wgj – SaFtsz (mutant)
- 3v3t – Ftsz – Clostridium botulinum
- 4e6e – Ftsz – Thermobifida fusca
- Ftsz binary complexes
- 2r75 – AaFtsz + 8-morpholino-GTP
- 1ofu – PaFtsz + SULA – Pseudomonas aeruginosa
- 2vaw - PaFtsz + GDP
- 1rlu, 2q1y – MtFtsz + γ-S-GTP – Mycobacterium tuberculosis
- 4b45 - HvFtsz + γ-S-GTP – Haloferax volcanii
- 4b46 - VoFtsz + GDP
- 1rq7, 4kwe - MtFtsz + GDP
- 1rq2, 2q1x – MtFtsz + citrate
- 1w58 – MjFtsz + GMP-CPP
- 1w5b - MjFtsz + GTP
- 2vap - MjFtsz + GDP
- 2rhh, 2rhj – BsFtsz + sulfate
- 2rhl – BsFtsz + GDP
- 2rho - BsFtsz + γ-S-GTP
- 4u39 - BsFtsz + cell division factor
- 3vo8, 3voa - SaFtsz + GDP
- 3wgl, 3wgk - SaFtsz (mutant) + GDP
- 3wgm - SaFtsz (mutant) + GTP
- 3wgn - SaFtsz + γ-S-GTP
- 3vob, 4dxd - SaFtsz + GDP + inhibitor
- 1f47 – EcFtsz + EcZipa – Escherichia coli
- 4m8i - Ftsz + GDP – Staphylococcus epidermidis
References
