4x2q: Difference between revisions

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'''Unreleased structure'''
==Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2==
 
<StructureSection load='4x2q' size='340' side='right' caption='[[4x2q]], [[Resolution|resolution]] 2.94&Aring;' scene=''>
The entry 4x2q is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4x2q]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X2Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X2Q FirstGlance]. <br>
Authors: Stenkamp, R.E., Le Trong, I., Amory, J.K., Paik, J., Goldstein, A.S.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Retinal_dehydrogenase Retinal dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.36 1.2.1.36] </span></td></tr>
Description: Crystal Structure of Human Aldehyde Dehydrogenase, ALDH1a2
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x2q OCA], [http://pdbe.org/4x2q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x2q RCSB], [http://www.ebi.ac.uk/pdbsum/4x2q PDBsum]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
[[Category: Stenkamp, R.E]]
== Function ==
[[http://www.uniprot.org/uniprot/AL1A2_HUMAN AL1A2_HUMAN]] Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity).  
__TOC__
</StructureSection>
[[Category: Retinal dehydrogenase]]
[[Category: Amory, J K]]
[[Category: Goldstein, A S]]
[[Category: Paik, J]]
[[Category: Paik, J]]
[[Category: Goldstein, A.S]]
[[Category: Stenkamp, R E]]
[[Category: Amory, J.K]]
[[Category: Trong, I Le]]
[[Category: Le Trong, I]]
[[Category: Dehydrogenase]]
[[Category: Isozyme]]
[[Category: Oxidoreductase]]
[[Category: Spermatogenesis]]
[[Category: Testis]]
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