Catalase: Difference between revisions

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'''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT). '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a heme group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH). '''Catalase-phenol oxidase''' (CATPO) is a heme-containing CAT which shows phenol oxidase activity.<ref>PMID:~~21524057~~</ref>

'''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT).<ref>PMID:21524057</ref> '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a heme group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH).<ref>PMID:15231843</ref> '''Catalase-phenol oxidase''' (CATPO) is a heme-containing CAT which shows phenol oxidase activity.<ref>PMID:22370948</ref>

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Revision as of 08:59, 6 December 2015 view source Michal Harel (talk \| contribs) 32,831 edits No edit summary ← Older edit		Revision as of 09:04, 6 December 2015 view source Michal Harel (talk \| contribs) 32,831 edits No edit summary Newer edit →
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	<StructureSection load='1gge' size='350' side='right' scene='46/467276/Cv/1' caption='E. coli catalase Hpii tetramer showing the heme group, [[1gge]]'>		<StructureSection load='1gge' size='350' side='right' scene='46/467276/Cv/1' caption='E. coli catalase Hpii tetramer showing the heme group, [[1gge]]'>

	'''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT). '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a heme group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH). '''Catalase-phenol oxidase''' (CATPO) is a heme-containing CAT which shows phenol oxidase activity.<ref>PMID:~~21524057~~</ref>		'''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT).<ref>PMID:21524057</ref> '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a heme group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH).<ref>PMID:15231843</ref> '''Catalase-phenol oxidase''' (CATPO) is a heme-containing CAT which shows phenol oxidase activity.<ref>PMID:22370948</ref>