Chitinase: Difference between revisions
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<StructureSection load='3wh1' size='350' side='right' caption='Chitinase A complex with (GlcNac)4 (stick model) and ethylene glycol (PDB entry [[3wh1]])' scene=''> | <StructureSection load='3wh1' size='350' side='right' caption='Chitinase A complex with (GlcNac)4 (stick model) and ethylene glycol (PDB entry [[3wh1]])' scene=''> | ||
__TOC__ | __TOC__ | ||
== Function == | == Function == | ||
[[Chitinase]]s cleave the beta-1-4-glycosidic bond between the N-acetyl-D-glucosamine units of which chitin is comprised. Chitinases are present in plants, bacteria and fungi. The first chitinase structures were solved in 1994, from a bacterium ([[1ctn]]) and a plant ([[2hvm]]). A mechanism for chitin cleavage was proposed based on several structures and was later confirmed. | [[Chitinase]]s cleave the beta-1-4-glycosidic bond between the N-acetyl-D-glucosamine units of which chitin is comprised. Chitinases are present in plants, bacteria and fungi. The first chitinase structures were solved in 1994, from a bacterium ([[1ctn]]) and a plant ([[2hvm]]). A mechanism for chitin cleavage was proposed based on several structures and was later confirmed. <ref>PMID:21054166</ref> | ||
==Disease == | ==Disease == | ||
